226: Cell-free DNA fetal fraction and pregnancy outcome
نویسندگان
چکیده
منابع مشابه
Cell-free fetal DNA and pregnancy-related complications (Review)
Cell‑free fetal DNA (cff‑DNA) is a novel promising biomarker that has been applied in various aspects of obstetrical research, notably in prenatal diagnosis and complicated pregnancies. It is easily detected by semi‑quantitative PCR for the SRY target gene. It is well recognized that the levels of circulating cff‑DNA play a role in various complications of pregnancy. In this review, we explore ...
متن کاملIntroducing a New and Simple Protocol for Capillary Electrophoresis of Cell Free Fetal Double Stranded DNA
Isolation of cell free fetal DNA (cffDNA) from maternal serum usually leads to very low concentrations of DNA impeding further resolving through conventional methods of electrophoresis. Although several protocols have been described for capillary electrophoresis (CE) of double stranded DNA, they usually need using special polymers or coated capillaries which degrade over time. Herein, we propos...
متن کاملFetal RHD Genotyping Using Real-Time Polymerase Chain Reaction Analysis of Cell-Free Fetal DNA in Pregnancy of RhD Negative Women in South of Iran
Objective Maternal-fetal RhD antigen incompatibility causes approximately 50% of clinically significant alloimmunization cases. The routine use of prophylactic anti-D immunoglobulin has dramatically reduced hemolytic disease of the fetus and newborn. Recently, fetal RHD genotyping in RhD negative pregnant women has been suggested for appropriate use of anti-D immunoglobulin antenatal prophylaxi...
متن کاملEarly Prediction of Hypertensive Disorders of Pregnancy Using Cell-Free Fetal DNA, Cell-Free Total DNA, and Biochemical Markers.
OBJECTIVE To evaluate the predictive value of separate and combined tests using cell-free fetal DNA (cffDNA), cell-free total DNA (cfDNA), and biochemical markers for the early detection of pregnancies with hypertensive disorders. METHODS A nested case-control study was conducted with 135 singleton pregnancies including 17 gestational hypertension cases, 34 preeclampsia (PE) cases, and 84 con...
متن کاملTeenage pregnancy and fetal outcome
Background: pregnancy in teenagers is not free of risks. The risk of low birth weight (LBW) and preterm delivery is particularly high among teenagers. LBW is significantly higher in young teenagers aged 13–19 years. Objectives: Evaluation of fetal outcome in teenage pregnancy in Assiut governorate, Egypt. Patients and methods: This study was conducted in the department of obstetrics and gynecol...
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2020
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2019.11.242